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KMID : 0364019970300030247
Korean Journal of Thoracic and Cardiovascular Surgery
1997 Volume.30 No. 3 p.247 ~ p.252
Development and Animal Tests of Pneumatic Ventricular Assist Device
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Abstract
Ten acute and chronic in vivo studies were utilized to develop a pneumatic ventricular assist device (VAD) as a bridge to heart transplantation or a circulatory assist device for patient with end-stage heart disease or poor myocardial function
after
cardiac surgery. Two sizes of blood pump of 70cc for adult patients and 34cc for pediatric were implanted in the animals. Ventricle of blood pump was made from the polyurethane to enhance antithrombogenecity. The VAD was implanted between the
left
atrium and the descending aorta. Average flow rate was 2.38 L/min for adult and 0.41 L/min for pediatric VAD at the rate of 60 bpm. The duration of support ranged from 1 to 26 hors. The most frequent complication was bleeding. Main causes of were
heart
failure and respiratory failure. The device function was good for short term use. Studies to date suggest that, with further refinement, a reliable long term VAD that will have clinical application can be developed.
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